Papules on the face
The differential diagnoses of facial papules is one of the classic differentials in dermatology.Usually a distinction is made on the basis of site and this is illustrated below.Benign lesions such as dermal nevi,sebaceous hyperplasia,plane warts,molluscum contagiosum,angiofibroma of the nose and syringomas around the eyes are the commonest lesions.In white people Bccs present looking like dermal nevi until they break down centrally,ulcerate and crust.Seborrhoeic keratoses are not always brown and malignant melanoma is not always black.Xanthelasma is common around the eyelids.
The rarer papules such as trichoepitheliomas and peri follicular fibromas may need a biopsy for diagnosis.
SIGN DIP MEN Overview of Papules
This is an extremely difficult area to give an all encompassing nemonic but SIGN DIP LAPPIS can be used where L=Lichen etc,A=Adnexae,P=Pediculosis,P=Perforating diseases,I=Infiltrates xanthoma etc,and S=Syndromes Grover’s,Darier’s, Albopapuloid EB etc
It is probably best to view the differential diagnosis of papules in particular situations
Monomorphic micropapules in a group Lichen nitidus,keratosis spinulosa,follicular eczema,follicular mucinosis,lichen scrofulosorum,sarcoidosis,lichen planus,keratosis pilaris
Polymorphic papules with necrosis Pityriasis lichenoides ,lymphomatoid papulosis,papulonecrotic tuberculid,Wegener’s granuloma,allergic granulomatosis,leukocytoclastic vasculitis,insect bites,acne necrotica,acnitis.
Keratotic papules forming rings or arciform lesions porokeratoses,perforating collagenoses,Kyrles disease,Elastosis perforans serpiginosa
Inflammatory papular dermatitis in children Gianoti Crosti syndrome,Papular acral located syndrome,papular urticaria,frictional dermatitis,Bindii dermatitis,caterpillar hairs,mite bites,benign cephalic histiocytosis
Facial adnexal papules Syringoma,trichoepithelioma,pilomatricoma,adenoma sebaceum,benign cephalic histiocytosis,Cowden’s syndrome
Eyelid Papules Milia,molluscum contagiosum,xanthoma,xanthogranuoma,amyloid,trichoepithelioma,Syringomas,acnitis,Cowden’s,Lipoid proteinosis,papular mucinosis
Multiple papules in the mouth Cowdens,Darier’s,Goltz,florid oral papillomatosis,xanthoma disseminatum,reticulo histiocytosis,lipoid proteinosis,adenoma sebaceum,drugs,pyostomatitis vegetans,verrucous carcinoma
Acral papules warts,Gianotti-Crosti,Cowden’s,Multicentric reticulohistiocytosis,epidermodysplasia verruciformis,viral infection
Follicular Papules Keratosis pilaris,lichen spinulosus,lichen planopilaris,Pityriasis rubra pilaris,lichen sclerosus,follicular mucinosis,discoid lupus erythematosus,vitamin d deficiency,fatty acid deficiency
SIGN DIP NIGL
N Nutritional Vit A,Vit C,essential fatty acid deficiency
I Infiltrates
G Genodermatoses Darier’s,Downs,Kyrles.
L Lichenoid
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