Flexures Nodules

Nodules in the flexures

Inflammatory nodules in the flexures should make you think of hidradenitis suppurativa with the associated sinuses and discharge or if solitary a furuncle and abscess.Pilonidal cysts and sinuses are common in the gluteal areas and natal cleft.Deep nodules in the groin may be lymphadenopathy secondary to lymphoma,other malignancy,lymphogranuloma venereum or secondary syphilis.Langerhans cell histiocytosis occasionally presents with nodules in the axillae and groin.

Hidradenitis suppurativa

SIGN DIP MEN    Nodules Overview

 

S-Squamous   Many of the infective nodules below will have a rough surface 

 

I-Infective          Deep fungal infections particularly Chromoblastomycosis and Sporotrichosis,Tuberculosis,Atypical mycobacterial ,Leishmaniasis,Syphilis,Leprosy,Orf,Milker’s nodules,

 

G-Granulomatous    Sarcoidosis,Granuloma annulare,Foreign body,Erythema elevatum diutinum,Rheumatoid nodule,Granuloma faciale,Panniculitis,Xanthogranuloma

 

N-Neoplastic    Benign Tumours such as sebaceous cysts,dermatofibroma,lipoma .More aggresive tumours such as  Basal cell carcinoma,Squamous cell carcinoma,Keratoacanthoma,Metastases,Merkel cell,Melanoma,Atypical fibroxanthoma,Mycosis fungoides,B cell lymphoma,Lymphocytoma,Angiolymphoid hyperplasia with eosinophilia,Angiosarcoma,Lymphangiosarcoma,Dermatofibrosarcoma protuberans,Cylindroma

 

D-Drugs    Iodides,Bromides,Phenytoin,Dapsone

 

I-Immunological   Erythema nodosum ,Sweet’s syndrome,Kimuras disease

 

P-Physical    Prurigo nodularis, Pyogenic granuloma,Digital myxoid cyst,Chilblains(Perniosis)

 

M-Metabolic   Xanthomas, Gouty tophi,Tumoral calcinosis,Mucinoses

 

E-Endocrine    Pretibial myxedema,

 

N-Nutritional

 

Others     Painful nodules   Multiple familial leiomyomas,Spiradenoma,Glomus tumour,Angiolipoma,Blue rubber bleb nevus ,Neuroma,Neurilemmoma,Keloid,Granular cell tumour,Dermatofibrosarcoma protuberans, Bleeding into a dermatofibroma